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Behaviour change techniques targeting both diet and physical activity in type 2 diabetes: A systematic review and meta-analysis.

Cradock (2017a)
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Changing diet and physical activity behaviour is one of the cornerstones of type 2 diabetes treatment, but changing behaviour is challenging. The objective of this study was to identify behaviour change techniques (BCTs) and intervention features of dietary and physical activity interventions for patients with type 2 diabetes that are associated with changes in HbA1c and body weight. We performed a systematic review of papers published between 1975-2015 describing randomised controlled trials (RCTs) that focused exclusively on both diet and physical activity. The constituent BCTs, intervention features and methodological rigour of these interventions were evaluated. Changes in HbA1c and body weight were meta-analysed and examined in relation to use of BCTs. Thirteen RCTs were identified. Meta-analyses revealed reductions in HbA1c at 3, 6, 12 and 24months of -1.11% (12mmol/mol), -0.67% (7mmol/mol), -0.28% (3mmol/mol) and -0.26% (2mmol/mol) with an overall reduction of -0.53% (6mmol/mol [95% CI -0.74 to -0.32, P < 0.00001]) in intervention groups compared to control groups. Meta-analyses also showed a reduction in body weight of -2.7kg, -3.64kg, -3.77kg and -3.18kg at 3, 6, 12 and 24months, overall reduction was -3.73kg (95% CI -6.09 to -1.37kg, P = 0.002). Four of 46 BCTs identified were associated with >0.3% reduction in HbA1c: instruction on how to perform a behaviour, behavioural practice/rehearsal, demonstration of the behaviour and action planning, as were intervention features supervised physical activity, group sessions, contact with an exercise physiologist, contact with an exercise physiologist and a dietitian, baseline HbA1c >8% and interventions of greater frequency and intensity. Diet and physical activity interventions achieved clinically significant reductions in HbA1c at three and six months, but not at 12 and 24months. Specific BCTs and intervention features identified may inform more effective structured lifestyle intervention treatment strategies for type 2 diabetes.